“no human chemist can yet match what a single jellyfish gene directs: 238 ordered condensations + 1 cyclization + 1 oxidation, all done in a few minutes in aerated water with no protecting groups, only one slightly toxic byproduct, and essentially 100% yield of an extremely useful product that literally glows green. Corals produce yellow and red fluorescent proteins with the same chemistry plus one extra oxidation. Yet coral reefs are also under world-wide jeopardy, due to acidification and warming of the oceans. So my final thanks are to both the jellyfish and corals: long may they have intact habitats in which to shine” Roger Y. Tsien’s speech at the Nobel banquet of 2008
Martin Chalfie, Osamu Shimomura, and Roger Y. Tsien were awarded the 2008 Nobel Prize in Chemistry on 10 October 2008 for their discovery and development of the green fluorescent protein(GFP).
the research of the Nobel prize winning molecular biologists that offered new hope for better antibiotics against pathogenic organisms,offer better knowledge of cellular transport mechanisms, and greater understanding of biological and human systems like it has never been!GFP expresses its fluorescent properties in vitro (in a dish), or even in vivo (in the living organism.,and can be used as a marker to study living systems while it maintains its glow of green ,blue or red as adapted.GFP is now established as an excellent gene tag or protein tag. GFP can be fused to a protein of interest, and fluorescence can be tracked within a cell to study its localization and behaviour.
the jellyfish may change the color of its bio-luminescence with depth. However, a collapse in the population of jellyfish in Friday Harbor, where GFP was originally discovered, has hampered further study of the role of GFP in the jellyfish’s natural environment. Bio luminescent organisms are found world wide. For example, the so called “phosphorescence” in sea water is observed in all oceans, mainly densely in bays and coral reefs, where high concentrations of nutrients,Calcium n Magnesium, promote blooms of the responsible organisms.we however observe that corals and pearls have been described as part of the favours of Allah and we are getting to know better!
“He has let free the two seas (salt and fresh water), meeting together:
Between them is a Barrier which none of them transgress:
Then which of the favours of your Lord will ye deny?
Out of them come both Pearls and Coral:
Then which of the favours of your Lord will ye deny? ” Quran 55 v19-23